Germs, germs, germs. They are one of the minor factors that are involved with the big question. These kind of germs or diseases are from the domesticated animals. However, they do make a big advantage in conquests. Smallpox, europeans mostly had them since there were lots of domesticated animals and a lot were killed. Due to this, they (europeans) were immune to smallpox. On the other hand, other civilizations for an example the Incans never came to smallpox and never had problems with them since they only had the llamas as there domesticated animal which are not so full of germs. (meaning that they didn't even know that they were sick and that they even existed and having no cure to smallpox) So they all died out due to the contagious and the epidemic smallpox and other minor diseases that the spaniards didn't even know that they had.
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